Your GPU's PCIe generation doesn't matter — except when it does
PCIe 3.0 or 4.0 doesn't matter for your GPU, until this happens

Nvidia and AMD haven't stopped pushing 8GB VRAM GPUs to the masses, but at least there's more awareness than before about the pitfalls of insufficient VRAM. While many users might know what running out of VRAM looks like, something that people with older PCs will ignore is the impact of insufficient VRAM on GPUs running on PCIe 3.0. If you have an AMD Ryzen 2000, Intel Core 10th Gen, or older CPU, buying a brand-new 8GB VRAM GPU should be the last thing you should be thinking about.